Course Structure

Evidence Based Medicine, what is it?
What is Critical Appraisal?
How to find papers to answer your question?
How a paper is structured
Different forms of research
Different terminology used to describe research designs
Different categories of evidence
Hierarchy of evidence
Further terminology to be aware of
Statistical methods
Being Aware of Outcomes
Diagnostic studies
Terminology to be aware of in a diagnostic paper
Likelihood ratios and area under the curve
Critical Appraisal of a Diagnostic Study
Therapeutic studies
Treatment effect
Critical Appraisal of a Therapeutic Study
Final Quiz
Click here for more detail on the course structure

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6 months membership to the Critical Appraisal Course

£95.00

6 months membership to an online critical appraisal course.

Delivered via web hosted podcasts and online questions from the team behind TheResusRoom podcast.

See below for full details.

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Description

The course will enable the user to read, understand and apply appropriate scientific research to their patients through critical appraisal.

Gives you unlimited access to the course for 6 months on any/all of your devices using your personal membership login.

Over 3 hours of web hosted podcasts, over 100 online questions to support understanding and retention of concepts and definitions.

Your personal certificate of course completion reflecting the anticipated completion time of 6 hours.

Delivered by the team from TheResusRoom podcast, a 5* rated iTunes podcast centred on evidenced based medicine in emergency care.

The course covers the following 19 sections

Evidence Based Medicine, what is it

  • Examples of great evidence changing practice
  • Examples of poor evidence changing practice

What is Critical Appraisal

  • PICO
  • Internal validity
  • External validity
  • Clinical significance

How to find papers to answer your question

  • MEDLINE, EMBASE, CINAHL etc
  • Grey literature

How a paper is structured

  • Authors
  • Abstract
  • Introduction
  • Methods
  • Results
  • Discussion

Different forms of research

  • Observational descriptive
  • Observational analytical
  • Experimental
  • Qualitative

Different terminology used to describe research designs

  • Cross sectional
  • Longitudinal
  • Retrospective
  • Prospective
  • Qualitative data
  • Quantitative data

Different categories of evidence

  • Expert opinion
  • Case report
  • Case series
  • Case control
  • Prospective Cohort Study
  • Retrospective Cohort Study
  • Controlled trials
  • Randomised control trials
  • Systematic Reviews
  • Meta-analyses

Hierarchy of evidence

  • Oxford levels of evidence

Further terminology to be aware of

  • Chance
  • Bias
  • Confounding
  • Internal Validity
  • External validity
  • Homogeneous
  • Heterogeneous

Statistical methods

  • Accuracy
  • Precision
  • Prevalence
  • Incidence
  • The hypothesis
  • P-values
  • Confidence intervals
  • False positives
  • False negatives
  • Power calculations

Being Aware of Outcomes

  • Statistically significant vs clinically significant
  • Secondary outcomes, beware

Diagnostic studies

  • The gold standard/reference standard
  • The population tested
  • Inter-observer reliability
  • Cost of the diagnostic test

Terminology to be aware of in a diagnostic paper

  • Case positive
  • Case negative
  • Test positive
  • Test negative
  • True positive
  • True negative
  • False positive
  • False negative
  • Sensitivity
  • Specificity
  • Positive predictive value
  • Negative predictive value

Likelihood ratios & area under the curve

  • Positive and negative likelihood ratios
  • Fagan’s nomogram
  • Categorical Likelihood ratios
  • Area under the curve

Critical Appraisal of a Diagnostic Study

  • Critical appraisal of the ADJUST-PE study
  • CASP diagnostic study checklist

Therapeutic studies

  • Randomisation
  • Allocation concealment
  • Blinding
  • Intention to treat & per-protocol analysis
  • Follow up
  • The outcome of interest
  • Composite outcomes

Treatment effect

  • Relative risk reduction (RRR)
  • Absolute risk reduction (ARR)
  • NNT

 Critical Appraisal of a Therapeutic Study

  • Critical appraisal of the PEITHO trial
  • CASP RCT check list checklist

Final Assessment

  • Online assessment via true/false questions
  • CPD certificate generation

 

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